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STEMCELL Technologies Ionomycin | B-LABO France
STEMCELL Technologies Ionomycin
Réf. : BL-RE-126728Réf. fabricant : 17180262 1 mg
236,25 € HT
Calcium ionophore
CAS
56092-81-0; 64-17-5
Synonyme
SQ 23377
Quantité
1 mg
Formule moléculaire
C41H72O9
Pureté
≥98%
Marque
STEMCELL Technologies
Caractéristiques principales
Ionomycin is a potent and selective calcium ionophore derived from Streptomyces conglobatus (Liu et al.) It is used as a research tool to rapidly raise the intracellular level of calcium, and to study calcium transport across biological membranes by inducing the release of cytosolic calcium stores (Morgan & Jacob; Yoshida & Plant)
Ionomycin is a more effective Ca++ ionophore than A23187, but less effective at binding and carrying Mg++ (Liu & Hermann)
Ionomycin is able to activate and prime the polymorphonuclear neutrophil (PMN) oxidase (Elzi et al.), and is used in conjunction with Phorbol 12-myristate 13-acetate (PMA; Catalog #74042) for the activation of T cells (IC50 = 5.8 nM; Caraher et al.; Zhang et al.) This product is supplied as a 10 mg/mL solution in ethanol
Activates T cells from human, mouse, or rat sources, in combination with PMA, to express cytokines including IL-17, IL-4, IL-10, and IL-2 (Caraher et al.; Harrington et al.; Parrish-Novak et al.)
Caractéristiques techniques
Marque
STEMCELL Technologies
Réf. B-LABO
BL-RE-126728
Réf. fabricant
17180262
CAS
56092-81-0; 64-17-5
Synonyme
SQ 23377
Quantité
1 mg
Formule moléculaire
C<sub>41</sub>H<sub>72</sub>O<sub>9</sub>
Pureté
≥98%
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