"/> STEMCELL Technologies UM729 | B-LABO France

STEMCELL Technologies UM729

Réf. : BL-RE-126752Réf. fabricant : 17109251 250 μg of active compound
305,10 € HT

Pyrimido-indole derivative that enhances HSC self-renewal in vitro

Synonyme
UM-729
Quantité
250 μg of active compound
Formule moléculaire
C20H25N5O2 · X HCl [X H2O]
Pureté
≥95%
Marque
STEMCELL Technologies

Caractéristiques principales

  • UM729 is a pyrimido-[4,5-b]-indole derivative which enhances the self-renewal of human hematopoietic stem cells in vitro
  • UM729 does not inhibit the aryl hydrocarbon receptor (AHR) pathway, but has been shown to collaborate with AHR antagonists in preventing differentiation of acute myeloid leukemia (AML) cells in culture
  • Enhances human hematopoietic stem cell self-renewal in vitro (Fares et al.)
  • Collaborates with StemRegenin 1 (SR1) in preventing differentiation of AML cells in culture (Pabst et al.)

Caractéristiques techniques

MarqueSTEMCELL Technologies
Réf. B-LABOBL-RE-126752
Réf. fabricant17109251
SynonymeUM-729
Quantité250 μg of active compound
Formule moléculaireC<sub>20</sub>H<sub>25</sub>N<sub>5</sub>O<sub>2</sub> · X HCl [X H2O]
Pureté≥95%
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