Sinefungin is a DNA methyltransferase (DNMT) inhibitor (IC50 = 0.1 - 20 μM; Copeland et al.) and an analog of the methyl donor S-adenosyl-L-methionine (SAM; Nolan; Horiuchi et al.)
Antiparasitic activity against malarial, trypanosomal, and leishmanial species (Nolan; Trager et al.; Dube et al.)
Inhibits Newcastle disease and vaccinia virus multiplication (Pugh et al.)
Inhibits pneumococcal biofilm growth in vitro and colonization in an in vivo rat model (Yadav et al.)
Caractéristiques techniques
Marque
STEMCELL Technologies
Réf. B-LABO
BL-RE-126812
Réf. fabricant
17110282
CAS
58944-73-3
Synonyme
A 9145; Antibiotic 32232RP; Antibiotic A 9145; RP 32232
