HA-100 is an isoquinoline compound with an added piperazinylsulfonyl group that acts as an inhibitor of protein kinases (PKs), including PKA, PKC, and PKG (IC50 = 8, 12, and 4 μM, respectively) (Hagiwara et al.)
Increases human fibroblast reprogramming efficiency with PD0325901, CHIR99021, A83-01 and hLIF (Yu et al.)
Improves single cell survival and supports high cloning efficiency in human pluripotent stem cell cultures (Chen et al.)
