CHIPOpt is a CHIP/STUB1 E3 ligase inhibitor.
In vitro
, CHIPOpt decreases phosphorylated tau ubiquitination, with little effect on unmodified tau. In Thioflavin T assays, CHIPOpt inhibits the ability of CHIP to suppress phosphorylated tau aggregation. FITC-CHIPOp (Cat. No. 8045), a fluorescent CHIPOpt, is also available.
Caractéristiques techniques
| Marque | Tocris Bioscience |
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| Réf. B-LABO | BL-RE-166565 |
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| Réf. fabricant | 30130466 |
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| Pureté | 0.95 |
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| Contenu et stockage | Store at -20°C |
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| Poids moléculaire | 757.84 |
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| Quantité | 1 mg |
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