DiscoverX ABT-737
478,50 € HT
ABT-737 is an antagonist for BCL2 and BCL2L1. Provided as 5mg of dry powder.
- Quantité
- 5 mg
- Marque
- DiscoverX
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ABT-737 is an antagonist for BCL2 and BCL2L1. Provided as 5mg of dry powder.
ABT-737 is a small molecule BH3 mimetic inhibitor of the anti-apoptotic members of the BCL-2 family, selective for BCL-2, BCL-XL, and BCL-W. Developed by Abbvie, it failed in clinical trials due to toxicity issues, but was proven efficacious with various radiation therapies in triggering apoptosis in cancer cells and xenografts. Provided as 5mg of dry powder.
| Marque | DiscoverX |
|---|---|
| Réf. B-LABO | BL-RE-170230 |
| Réf. fabricant | 17332479 |
| Quantité | 5 mg |