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Tocris Bioscience™ Exendin-4

Name: Tocris Bioscience™ Exendin-4
Brand: Tocris Bioscience
SKU: 18787186
Price: 476.23 EUR
Availability: InStock

Réf. : BL-RE-043417Réf. fabricant : 18787186 1 mg

476,23 € HT

Potent GLP-1 receptor agonist

Quantité: 1 mg
Marque: Tocris Bioscience

Exendin-4 is a high affinity glucagon-like peptide 1 (GLP-1) receptor agonist (Kd = 136 pM); originally isolated from

Heloderma suspectum

venom. Exendin-4 potently induces cAMP formation without stimulating amylase release in pancreatic acini. Potentiates glucose-induced insulin secretion in isolated rat islets. Exendin-4 protects against glutamate-induced neurotoxicity, and in a mouse model of metabolic imblance it reduces neuroinflammation and enhances long-term-potentiation.