"/> Tocris Bioscience™ Klotho-derived peptide 1 | B-LABO France

Tocris Bioscience™ Klotho-derived peptide 1

Réf. : BL-RE-043647Réf. fabricant : 18023882 1 mg
199,20 € HT

TGF-β receptor 2 (TβR2) binding peptide; disrupts the TGF-β/TβR2 interaction

Gene ID (Entrez)
9365
Pureté
95%
Contenu et stockage
Store at -20°C
Alias de gène
EC 3.2.1, EC 3.2.1.31, KL, klotho, TGFB2, TGFbeta, TGFbeta 2
Poids moléculaire
M.W. (Observed): 3228.48
Marque
Tocris Bioscience

Klotho-derived peptide 1 (KP1) is a peptide that binds to TGF-β receptor 2 (TβR2) (Kd = 1.4 μM). It inhibits TGF-β signaling by blocking TGF-β/TβR2 interaction. In mouse models of renal fibrosis, intravenous injection of KP1 results in its specific accumulation in the injured kidneys. It suppresses TGF-β signaling, repressing fibroblast activation and ameliorates kidney fibrosis

in vivo

.

Caractéristiques techniques

MarqueTocris Bioscience
Réf. B-LABOBL-RE-043647
Réf. fabricant18023882
Gene ID (Entrez)9365
Pureté95%
Contenu et stockageStore at -20°C
Alias de gèneEC 3.2.1, EC 3.2.1.31, KL, klotho, TGFB2, TGFbeta, TGFbeta 2
Poids moléculaireM.W. (Observed): 3228.48
Quantité1 mg
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