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Tocris Bioscience™ Decanoyl-RVKR-CMK

Name: Tocris Bioscience™ Decanoyl-RVKR-CMK
Brand: Tocris Bioscience
SKU: 18085062
Price: 254.53 EUR
Availability: InStock

Réf. : BL-RE-047466Réf. fabricant : 18085062 1 mg

254,53 € HT

Subtilisin/Kex2p-like proprotein convertase inhibitor

Quantité: 1 mg
Marque: Tocris Bioscience

Decanoyl-RVKR-CMK is a subtilisin/Kex2p-like proprotein convertase inhibitor; blocks activity of all seven convertases (PC1, PC2, PC4, PACE4, PC5, PC7 and furin). Abolishes proET-1 processing in endothelial cells; inhibits regulated secretion of the neuronal polypeptide VGF in PC12 cells. Inhibits cleavage of glycoprotein B of human cytomegalovirus. Also inhibits cleavage of SARS-CoV-2 spike protein by furin and blocks viral cell entry (IC50 = 57 nM in plaque reduction assay).