Tocris Bioscience™ Jingzhaotoxin III
469,75 € HT
Selective NaV1.5 channel blocker
- Pureté
- 0.95
- Quantité
- 100 μg
- Marque
- Tocris Bioscience
Jingzhaotoxin III is a selective blocker of NaV1.5 channels (IC50 = 348 nM); displays no effect on other isoforms, including NaV1.2, NaV1.4, NaV1.6 and NaV1.7. Thought to inhibit sodium channel activation by binding to the NaV1.5 S3-S4 linker of domain II. Selectively inhibits the activation of cardiac sodium channels, but has no effect on sodium channels in dorsal root ganglion neurons.
Caractéristiques techniques
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-050295 |
| Réf. fabricant | 18778257 |
| Pureté | 0.95 |
| Quantité | 100 μg |
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