"/> Tocris Bioscience™ SHU 9119 | B-LABO France

Tocris Bioscience™ SHU 9119

Name: Tocris Bioscience™ SHU 9119
Brand: Tocris Bioscience
SKU: 18064942
Price: 208.05 EUR
Availability: InStock

Réf. : BL-RE-050453Réf. fabricant : 18064942 1 mg

208,05 € HT

MC3 and MC4 antagonist; MC5 partial agonist

Pureté: 0.95
Quantité: 1 mg
Marque: Tocris Bioscience

SHU 9119 is a potent melanocortin MC3 and MC4 receptor antagonist (IC50 values are 0.23 and 0.06 nM respectively) and MC5 partial agonist (EC50 = 0.12 nM). Upregulates expression of genes promoting lipogenesis and triglyceride storage (SCD1, LPL, ACCα and FAS), increases triglyceride synthesis and promotes insulin resistance. Increases food intake, body weight and fat mass when administered centrally

in vivo