"/> Tocris Bioscience™ Obtustatin | B-LABO France

Tocris Bioscience™ Obtustatin

Name: Tocris Bioscience™ Obtustatin
Brand: Tocris Bioscience
SKU: 18728917
Price: 419.00 EUR
Availability: InStock

Réf. : BL-RE-054883Réf. fabricant : 18728917

419,00 € HT

Potent and selective α1β1 inhibitor

Pureté: 95%
CAS: 404882-00-4
Quantité: 100 μg
Marque: Tocris Bioscience

Obtustatin is a highly potent integrin α1β1 inhibitor (IC50 = 0.8 nM for α1β1 binding to type IV collagen). Selective for α1β1 over α2β1, αIIbβ3, αvβ3, α4β1, α5β6, α9β1 and α4β7. Inhibits FGF2-stimulated angiogenesis in the chicken chorioallantoic model. Displays antitumor efficacy in a synergistic mouse model of Lewis lung carcinoma; blocks human melanoma growth in nude mice.