Potent and selective VPAC2 agonist
Bay 55-9837 is a selective VPAC2 receptor agonist (EC50 values are 0.4, 100 and >1000 nM for VPAC2, VPAC1 and PAC1, respectively in a cAMP accumulation assay; IC50 values are 60, 8700 and >10000 nM for VPAC2, VPAC1 and PAC1, respectively in a competition binding assay). Stimulates glucose-dependent insulin secretion in isolated human pancreatic islets. Reduces HIV-1 viral replication and shows cooperative effects when given in conjunction with VPAC1 agonists.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-055946 |
| Réf. fabricant | 18797037 |
| Pureté | 95% |
| Contenu et stockage | Store at -20°C |
| Poids moléculaire | M.W. (Observed): 3742.29 |
| Quantité | 1 mg |
