FPR1, FPR2 and FPR3 receptor agonist
WKYMVm is a selective agonist for the formyl peptide receptors FPR1, FPR2 (EC50 = 75 pM) and FPR3 (EC50 = 3 nM), expressed on immune cells. Induces Ca2+ mobilization and superoxide production in, and chemotaxic migration of, monocytes and neutrophils. Also promotes monocyte survival through a PKC-, PI 3-kinase- and Akt-dependent pathway.
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-083366 |
| Réf. fabricant | 18786266 |
| Pureté | 0.95 |
| Contenu et stockage | Store at -20°C |
| Quantité | 1 mg |
