Competitive antagonist for Nogo-66 receptor; promotes neuron regeneration
Nogo-66 (1-40) is a peptide fragment corresponding to residues 1 - 40 of Nogo-66, the domain of the myelin protein Nogo that inhibits axonal outgrowth. Acts as a competitive antagonist at the Nogo-66 receptor (NgR); blocks Nogo-66- and CNS myelin-induced inhibition of axonal growth, but does not reduce myelin-associated glycoprotein (MAG) inhibition of neurite outgrowth
in vitro
. Promotes regeneration of hemisected spinal axons and locomotor recovery following spinal injury
in vivo
| Marque | Tocris Bioscience |
|---|---|
| Réf. B-LABO | BL-RE-083473 |
| Réf. fabricant | 18074942 |
| Pureté | 95% |
| Contenu et stockage | Store at -20°C |
| Quantité | 1 mg |
