"/> Tocris Bioscience™ ShK-Dap22 | B-LABO France

Tocris Bioscience™ ShK-Dap22

Name: Tocris Bioscience™ ShK-Dap22
Brand: Tocris Bioscience
SKU: 18768447
Price: 379.04 EUR
Availability: InStock

Réf. : BL-RE-085909Réf. fabricant : 18768447 100 μg

379,04 € HT

Extremely potent and selective KV1.3 blocker; suppresses T cell activation in vitro

Quantité: 100 μg
Marque: Tocris Bioscience

ShK-Dap22 is an extremely potent KV1.3 channel blocker (Kd = 23 pM for mKV1.3 currents). Selective for KV1.3 over other mammalian potassium channels (IC50 values are 23, 1800, 10500, 37000 and 39000 pM for mKV1.3, mKV1.1, hKV1.6, mKV1.4 and rKV1.2 respectively, and >100000 pM for hKV1.5, mKV1.7, hKV3.1, rKV3.4 and hKCa4). Suppresses T cell activation

(IC50 < 500 pM).