Used for Func, SDS-PAGE
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.[provided by RefSeq]
| Marque | Abnova |
|---|---|
| Réf. B-LABO | BL-RE-086244 |
| Réf. fabricant | 16068076 |
| Concentration | 0.2 mg/mL |
| À utiliser avec (application) | Functional Study, SDS-PAGE |
| Formule | In 50mM Tris-HCl, 300mM NaCl, 5mM CaCl |
| Identification génétique (Entrez) | 4312 |
| Poids moléculaire | 52-56kDa |
| Nom | MMP1 (Human) Native Protein |
| Méthode de préparation | Native protein purified from human fibroblasts |
| Méthode de purification | Affinity Chromatography/Ion Exchange Chromatography/Gelfiltration |
| Test du contrôle qualité | 15% SDS-PAGE Stained with Coomassie Blue |
| Quantité | 10 ug |
| Conditions de stockage | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| État réglementaire | RUO |
| Alias de gène | CLG/CLGN |
| Nom usuel | MMP1 |
| Symbole de gène(s) | MMP1 |
| Activité biologique | ≥ 100mU/mg (upon trypsin activation) |
| Espèces | Human |
| Marqueur de protéine | None |
| Système d’expression | Native protein purified from human fibroblasts |
| Forme | Liquid |
| Pureté ou qualité | >90% by SDS-PAGE |
