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Used for Func, SDS-PAGE
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.[provided by RefSeq]
Concentration : 0.2 mg/mL
À utiliser avec (application) : Functional Study, SDS-PAGE
Formule : In 50mM Tris-HCl, 300mM NaCl, 5mM CaCl
Identification génétique (Entrez) : 4312
Poids moléculaire : 52-56kDa
Nom : MMP1 (Human) Native Protein
Méthode de préparation : Native protein purified from human fibroblasts
Méthode de purification : Affinity Chromatography/Ion Exchange Chromatography/Gelfiltration
Test du contrôle qualité : 15% SDS-PAGE Stained with Coomassie Blue
Quantité : 10 ug
Conditions de stockage : Store at -80°C. Aliquot to avoid repeated freezing and thawing.
État réglementaire : RUO
Alias de gène : CLG/CLGN
Nom usuel : MMP1
Symbole de gène(s) : MMP1
Activité biologique : ≥ 100mU/mg (upon trypsin activation)
Espèces : Human
Marqueur de protéine : None
Système d’expression : Native protein purified from human fibroblasts
Forme : Liquid
Pureté ou qualité : >90% by SDS-PAGE
